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Our Reviews

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By subtopic:

Dementia and chronic cognitive impairment (200)
Hospital care (1)
Hospital design for older people with cognitive impairment including dementia and delirium: supporting inpatients and accompanying persons (protocol stage)
Interventions aimed at the causes of the disease (26)
AAB-001 - immunotherapy (1)
Intravenous immunoglobulin for Alzheimer's disease (protocol stage)
ACC-001 - immuno-conjugate (0)
Alcohol management (0)
Alpha Interferon (0)
Alzhemed (0)
Amantadine (0)
Anti-hypertensives management (0)
Aspirin (3)
Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease
Acetyl-l-carnitine for dementia
Aspirin for vascular dementia
Aspirin - high dose (0)
Cannabis (1)
Cannabinoids for the treatment of dementia
Chelating agents (1)
Metal protein attenuating compounds for the treatment of Alzheimer's dementia
Choto-San (0)
Coenzyme Q (0)
Curcumin (Turmeric, curry) (0)
Cyclophosphamide (0)
DHEA (0)
Diabetes management (1)
Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia
Diclofenac (NSAID) (0)
DMAE (dimenthylaminoethanol) (0)
Dimebon (1)
Latrepirdine for Alzheimer's disease
Doxycyline (0)
Etanercept (0)
Flurizan (0)
Folate (1)
Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people
Gilatide (0)
Green tea (0)
Huperzine A (3)
Huperzine A for mild cognitive impairment
Huperzine A for Alzheimer's disease
Huperzine A for vascular dementia
Ibuproven (NSAID) (1)
Ibuprofen for Alzheimer's disease
Indomethacin (NSAID) (1)
Indomethacin for Alzheimer's disease
Naproxen (NSAID) (0)
Nimodipine (1)
Nimodipine for primary degenerative, mixed and vascular dementia
NSAIDS (0)
Oestrogen (1)
Hormone replacement therapy to maintain cognitive function in women with dementia
Omega-3 Fish Oil (1)
Omega-3 fatty acids for the treatment of dementia
Peri-operative management (0)
Pregnenolone (0)
Procaine (Gerovital) (1)
Procaine treatments for cognition and dementia
Pyritinol (0)
Pyroglutamic acid (0)
Rifampin (0)
Rofecoxib (0)
SGS-742 (0)
Statins (Atorvastatin) (1)
Statins for the treatment of dementia
Tarenflurbil (0)
Thiamine (2)
Thiamine for Alzheimer's disease
Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Vaccines (AN-1792) (0)
Vitamin B supplements (0)
Vitamin B3 (Niacin) (0)
Vitamin B6 (Pyroxidine) (1)
Vitamin B6 for cognition
Vitamin B12 (1)
Vitamin B12 for cognition
Vitamin D derivative (0)
Vitamin E (1)
Vitamin E for Alzheimer's dementia and mild cognitive impairment
Wine (red) (0)
Xanomeline (0)
Xianlong (0)
Yi Zhi (1)
Yizhi capsule for vascular dementia
Zhiling (1)
Zhiling decoction for vascular dementia
Interventions aimed at interrupting disease processes (69)
ABT-418 (0)
Acetyl-l-carnitine (1)
Acetyl-l-carnitine for dementia
AF 102B (0)
Almitrine-Raubasine (1)
Almitrine-Raubasine combination for dementia
Alpha-lipoic acid (1)
Alpha lipoic acid for dementia
Alzhemed (0)
Ampalex (CX 516) (0)
AIP 001 (0)
Anapsos (0)
Aniracetam (0)
Arecholine (0)
Bacopa monniera (0)
Besipirdine (HP 749) (0)
Beta & Gamma-Secretase Inhibitors (0)
Cannabis (0)
CDP-choline (2)
Pharmacotherapy for chronic cognitive impairment in traumatic brain injury
Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly
Cerebrolysin (2)
Cerebrolysin for Alzheimer's disease (protocol stage)
Cerebrolysin for vascular dementia
Cerestat (Aptigane) (0)
Chlorpromazine (0)
Clioquinol (1)
Metal protein attenuating compounds for the treatment of Alzheimer's dementia
Colostrinin (0)
Cyclandelate (0)
Dapsone (0)
D-cycloserine (1)
D-cycloserine for Alzheimer's disease
Desferrioxamine mesylate (0)
Denbufylline (0)
Donepezil (9)
Cholinesterase inhibitors for Alzheimer's disease
Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease
Donepezil for dementia due to Alzheimer's disease
Pharmacotherapy for chronic cognitive impairment in traumatic brain injury
Donepezil for vascular cognitive impairment
Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta-analysis
Cholinesterase inhibitors for Parkinson's disease dementia
Withdrawal or continuation of cholinesterase inhibitors or memantine or both, in people with dementia
Cholinesterase inhibitors for rarer dementias associated with neurological conditions
Ebselen (DR-3305) (0)
Eptastigmine (0)
Fluphenazine (Modecate) (0)
Galantamine (8)
Cholinesterase inhibitors for Alzheimer's disease
Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease
Pharmacotherapy for chronic cognitive impairment in traumatic brain injury
Galantamine for Alzheimer's disease and mild cognitive impairment
Galantamine for vascular cognitive impairment
Cholinesterase inhibitors for Parkinson's disease dementia
Withdrawal or continuation of cholinesterase inhibitors or memantine or both, in people with dementia
Cholinesterase inhibitors for rarer dementias associated with neurological conditions
Gastrodine (0)
Ginkgo biloba (2)
Ginkgo biloba for cognitive impairment and dementia (protocol stage)
Ginkgo biloba for cognitive impairment and dementia
Ginseng (1)
Ginseng for cognition
GSK-3 (0)
Homoeopathy (1)
Homeopathy for dementia
Huperzine (3)
Huperzine A for mild cognitive impairment
Huperzine A for Alzheimer's disease
Huperzine A for vascular dementia
Hydergine (1)
Hydergine for dementia
Idebenone (0)
Indomethacin (1)
Indomethacin for Alzheimer's disease
Lazabemide (0)
Lecithin (1)
Lecithin for dementia and cognitive impairment
Leuprolide (0)
Linopirdine (DUP996) (0)
Lithium (0)
LU25-109 (0)
MKC-231 (0)
Memantine (2)
Memantine for dementia
Withdrawal or continuation of cholinesterase inhibitors or memantine or both, in people with dementia
Memric (SB 202026) (0)
Melatonin (1)
Melatonin for the treatment of dementia
Metrifonate (1)
Metrifonate for Alzheimer's disease
Milacemide (0)
Milameline (0)
Moclobemide (0)
Montirelin (NS-3) (0)
Naftidrofuryl (1)
Naftidrofuryl for dementia
Naproxen (0)
Nebracetam (0)
Nefiracetam (0)
Neotrofin (AIT 082) (0)
Neromexine (0)
Nicaraven (AVS) (0)
Nicergoline (1)
Nicergoline for dementia and other age associated forms of cognitive impairment
Nicotine (1)
Nicotine for Alzheimer's disease
Nimodipine (1)
Nimodipine for primary degenerative, mixed and vascular dementia
NS2330 (0)
Oxiracetam (0)
Ondansetron (0)
Oxygen therapy (1)
Hyperbaric oxygen therapy for vascular dementia
Pentoxifylline (0)
Phenserine (0)
Physostigmine (1)
Pharmacotherapy for chronic cognitive impairment in traumatic brain injury
Picamilone (0)
Piracetam (1)
Piracetam for dementia or cognitive impairment
Posatirelin (0)
Propentofylline (1)
Propentofylline for dementia
Quilostigmine (S-12024) (0)
Quinacrine (0)
Rivastigmine (8)
Cholinesterase inhibitors for Alzheimer's disease
Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease
Pharmacotherapy for chronic cognitive impairment in traumatic brain injury
Cholinesterase inhibitors for Parkinson's disease dementia
Rivastigmine for Alzheimer's disease
Rivastigmine for vascular cognitive impairment
Withdrawal or continuation of cholinesterase inhibitors or memantine or both, in people with dementia
Cholinesterase inhibitors for rarer dementias associated with neurological conditions
Rofecoxib (0)
Sabeluzole (0)
SB 202026 (0)
Selegiline (1)
Selegiline for Alzheimer's disease
Senilex (0)
Shunts (3)
Endoscopic third ventriculostomy (ETV) for idiopathic normal pressure hydrocephalus (iNPH)
Shunting for idiopathic normal pressure hydrocephalus (protocol stage)
Shunting for normal pressure hydrocephalus (NPH)
SR 57746A (0)
Statins (1)
Statins for the prevention of dementia
Sunonacrine (0)
Tacrine (3)
Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease
Cholinesterase inhibitors for dementia with Lewy bodies
Cholinesterase inhibitors for Parkinson's disease dementia
Taltirelin (TA-0910) (0)
Thiazolidinediones (0)
Traditional chinese herbal medicine (1)
Traditional Chinese herbal medicine for vascular dementia
Velnacrine (1)
Velnacrine for Alzheimer's disease
Vinpocetine (1)
Vinpocetine for cognitive impairment and dementia
WAL-2014 (0)
Xanomeline (0)
Yi-Zhi-Jian-Shen-Jing (0)
Yi Zhi (1)
Yizhi capsule for vascular dementia
Xianlong (0)
Zhiling (1)
Zhiling decoction for vascular dementia
Management of manifestations of the disease (69)
Aggression (4)
Anti-psychotic withdrawal (1)
Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia
Carbamazepine (0)
Chlorpromazine (Largactil) (0)
Clopenthixol (Clopixol) (0)
Fluphenazine (Modecate) (0)
Lorazepam (0)
Melperone (0)
Oxazepam (0)
Promazine (0)
Sodium valproate (1)
Valproate preparations for agitation in dementia
Tiapride (0)
Thioridazine (1)
Thioridazine for dementia
Valproic acid (1)
Valproate preparations for agitation in dementia
Agitation (17)
Anti-psychotic withdrawal (2)
Psychosocial interventions for reducing antipsychotic medication in care home residents
Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia
Aripiprazole (1)
Atypical antipsychotics for aggression and psychosis in Alzheimer's disease
Benzodiazepines (0)
Cannabis derivatives (1)
Cannabinoids for the treatment of dementia
Carbamazepine (0)
Chlorpromazine (Largactil) (0)
Clopenthixol (Clopixol) (0)
Clozapine (1)
Atypical antipsychotics for aggression and psychosis in Alzheimer's disease
Diazepam (0)
Divalproex sodium (1)
Valproate preparations for agitation in dementia
Gabapentin (0)
Haloperidol (1)
Haloperidol for agitation in dementia
Lorazepam (0)
Melperone (0)
Music therapy (1)
Music-based therapeutic interventions for people with dementia
Olanzapine (1)
Atypical antipsychotics for aggression and psychosis in Alzheimer's disease
Opioids (1)
Opioids for agitation in dementia
Oxazepam (0)
Promazine (0)
Psychosocial interventions (0)
Quetiapine (1)
Atypical antipsychotics for aggression and psychosis in Alzheimer's disease
Reality orientation (0)
Reminiscence therapy (1)
Reminiscence therapy for dementia
Risperidone (1)
Atypical antipsychotics for aggression and psychosis in Alzheimer's disease
Thioridazine (1)
Thioridazine for dementia
Tiapride (0)
Trazodone (1)
Trazodone for agitation in dementia
Validation therapy (1)
Validation therapy for dementia
Valproic acid (1)
Valproate preparations for agitation in dementia
Anxiety (5)
Anti-psychotic withdrawal (1)
Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia
Cannabis derivatives (0)
Flurazepam (Dalmane) (0)
Gabapentin (0)
Music therapy (1)
Music-based therapeutic interventions for people with dementia
Psychosocial (1)
Psychological treatments for depression and anxiety in dementia and mild cognitive impairment
Reality orientation (0)
Reminiscence therapy (1)
Reminiscence therapy for dementia
Benzodiazepines (0)
Validation Therapy (1)
Validation therapy for dementia
Apathy (1)
Pharmacological interventions for apathy in Alzheimer's disease
Carer burden (5)
Cognitive and behavioural interventions (1)
Cognitive reframing for carers of people with dementia
Support (4)
Efficacy and experiences of telephone counselling for informal carers of people with dementia
Mindfulness-based stress reduction for family carers of people with dementia
Remotely delivered information, training and support for informal caregivers of people with dementia
Respite care for people with dementia and their carers
Psycho-educational interventions (0)
Delusions (1)
Anti-psychotic withdrawal (1)
Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia
Depression (18)
Amitriptyline (Lentizol) (1)
Antidepressants for treating depression in dementia
Amoxapine (1)
Antidepressants for treating depression in dementia
Anti depressants (2)
Antidepressants for agitation and psychosis in dementia
Antidepressants for treating depression in dementia
Citalopram (1)
Antidepressants for treating depression in dementia
Dothiepin (Prothiaden) (1)
Antidepressants for treating depression in dementia
Doxepin (Sinequan) (1)
Antidepressants for treating depression in dementia
Fluoxetine (Prozac) (1)
Antidepressants for treating depression in dementia
Imipramine (1)
Antidepressants for treating depression in dementia
Lofepramine (Gamanil) (1)
Antidepressants for treating depression in dementia
Mirtazipine (1)
Antidepressants for treating depression in dementia
Nefazodone (1)
Antidepressants for treating depression in dementia
Nortiptyline (Allegron) (1)
Antidepressants for treating depression in dementia
Paroxetine (Seroxat) (1)
Antidepressants for treating depression in dementia
Psychosocial (1)
Psychological treatments for depression and anxiety in dementia and mild cognitive impairment
Reboxetine (Edronax) (1)
Antidepressants for treating depression in dementia
Sertraline (Lustral) (1)
Antidepressants for treating depression in dementia
Sulpiride (1)
Antidepressants for treating depression in dementia
Epilepsy (0)
Investigational procedures (0)
neuroimaging (0)
rating scales (0)
Malnutrition (2)
Tube feeding (2)
Enteral tube feeding for people with severe dementia
Enteral tube feeding for older people with advanced dementia
Mobility (1)
Driving assessment (1)
Driving assessment for maintaining mobility and safety in drivers with dementia
Sleep problems (4)
Alprazolam (Xanax) (0)
Chloral Hydrate (Welldorm) (0)
Chlormethiazole (Heminevrin) (0)
Flurazepam (Dalmane) (0)
Light/photo therapy (1)
Light therapy for improving cognition, activities of daily living, sleep, challenging behaviour, and psychiatric disturbances in dementia
Melatonin (2)
Pharmacotherapies for sleep disturbances in dementia
Melatonin for the treatment of dementia
Non pharmacological interventions for sleep problems in peopl with dementia (1)
Non-pharmacological interventions for sleep disturbances in people with dementia (protocol stage)
Nitrazepam (0)
Psychosocial (0)
Temazepam (0)
Zopiclone (0)
Mood instability (1)
Anti-psychotic withdrawal (1)
Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia
Carbamazepine (0)
Sexual disinhibition (0)
Psychosis (7)
Anti-psychotic withdrawal (1)
Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia
Aripiprazole (1)
Atypical antipsychotics for aggression and psychosis in Alzheimer's disease
Carbamazepine (0)
Clozapine (1)
Atypical antipsychotics for aggression and psychosis in Alzheimer's disease
Olanzapine (1)
Atypical antipsychotics for aggression and psychosis in Alzheimer's disease
Psychosocial interventions (0)
Quetiapine (1)
Atypical antipsychotics for aggression and psychosis in Alzheimer's disease
Risperidone (1)
Atypical antipsychotics for aggression and psychosis in Alzheimer's disease
Sulpiride (0)
Thioridazine (1)
Thioridazine for dementia
Tiapride (0)
Wandering (3)
Domestic wandering (1)
-Non-pharmacological interventions for wandering of people with dementia in the domestic setting
Music Therapy (1)
Music-based therapeutic interventions for people with dementia
Reality orientation (0)
Subjective barriers (1)
Subjective barriers to prevent wandering of cognitively impaired people
Tiapride (0)
Rehabilitation and care (35)
Acupuncture (anxiety, depression, cognition) (1)
Acupuncture for vascular dementia
Art therapy (1)
Art therapy for people with dementia
Audiovisual stimulation (0)
Aquatic therapy (cognition, behavioural problems) (0)
Animal assisted therapy (agitation, well-being, memory function) (1)
Animal-assisted therapy for dementia
Aroma therapy (agitation) (1)
Aromatherapy for dementia
Care management and crisis resolution approaches (5)
Case management approaches to home support for people with dementia
Organisational interventions for promoting person-centred care for people with dementia (protocol stage)
Organizational interventions for promoting person-centred care for people with dementia (protocol stage)
Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery
Algorithm-based pain management for people with dementia in nursing homes
Cognitive behavioural therapy (1)
Cognitive reframing for carers of people with dementia
Cogntive rehabilitation (mood, memory training, wellbeing)) (3)
Cognitive rehabilitation for people with mild to moderate dementia (protocol stage)
Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia
Cognitive training for people with mild to moderate dementia
Cognitive Stimulation (1)
Cognitive stimulation to improve cognitive functioning in people with dementia
Dance therapy (0)
Family counseling (1)
Efficacy and experiences of telephone counselling for informal carers of people with dementia
Functional analysis of challenging behaviour (1)
Functional analysis-based interventions for challenging behaviour in dementia
Home care (0)
Light/Photo therapy (sundowning, sleep, agitation) (1)
Light therapy for improving cognition, activities of daily living, sleep, challenging behaviour, and psychiatric disturbances in dementia
Multidiciplinary team interventions (0)
Music Therapy (1)
Music-based therapeutic interventions for people with dementia
Occupational therapy (wellbeing, cognition) (2)
Personally tailored activities for improving psychosocial outcomes for people with dementia in long-term care
Personally tailored activities for improving psychosocial outcomes for people with dementia in community settings
Physical restraints (2)
Interventions for preventing and reducing the use of physical restraints in long-term geriatric care
Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings (protocol stage)
Physical therapy (1)
Exercise programs for people with dementia
Psychosocial therapy (0)
Reminiscence therapy (1)
Reminiscence therapy for dementia
Respite care (1)
Respite care for people with dementia and their carers
Snoezelen (behaviour, mood, cognition, wellbeing) (1)
Snoezelen for dementia
Special Care Units (1)
Special care units for dementia individuals with behavioural problems
Support groups for people with early stage dementia (0)
Telecare and assistive technology (2)
Assistive technology for memory support in dementia
Efficacy and experiences of telephone counselling for informal carers of people with dementia
Therapeutic touch (wellbeing, agitation, aggression) (1)
Massage and touch for dementia
Transcutaneous electrical nerve stimulation (TENS) ( cognition, depression, problem behaviour) (1)
Transcutaneous Electrical Nerve Stimulation (TENS) for dementia
Tube feeding (malnutrition, well being,functional state) (3)
Environmental and behavioural modifications for improving food and fluid intake in people with dementia
Modifying the consistency of food and fluids for swallowing difficulties in dementia
Enteral tube feeding for older people with advanced dementia
Validation therapy (aggression, agitation, depression, wellbeing) (1)
Validation therapy for dementia
Delirium (11)
Pharmacological Interventions (7)
Benzodiazepines (2)
Benzodiazepines for delirium
Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit
Memantine (0)
Phenothiazines (1)
Acepromazine (0)
Chlorpromazine (0)
Fluphenazine (0)
Mesorodazine (0)
Methotrimeprazine (0)
Perazine (0)
Perphenazine (0)
Promazine (0)
Promethazine (0)
Thioridazine (1)
Thioridazine for dementia
Trifluoperazine (0)
Triflupromazine (0)
Butyrophenones (0)
Azaperone (0)
Droperidol (0)
Haloperidol (0)
Spiperone (0)
Trifluperidol (0)
Minor thanquilisers (0)
Chlordiazepoxide (0)
Diazepam (0)
Chlormethiazole (0)
Atypical antipsychotics (2)
Antipsychotics for treatment of delirium in hospitalised non-ICU patients
Antipsychotics for agitation and psychosis in people with Alzheimer's disease and vascular dementia
Cholinesterase inhibitors (2)
Cholinesterase inhibitors for the treatment of delirium in non-ICU settings
Cholinesterase inhibitors for delirium
Non-pharmacological Interventions (4)
Environmental interventions (0)
Multidiscipinary team interventions (4)
Interventions for preventing delirium in older people in institutional long-term care
Interventions for preventing delirium in hospitalised non-ICU patients
Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients
Non-pharmacological interventions for managing delirium in hospitalised patients (protocol stage)
Oxygen (0)
Diagnosis (33)
Imaging techniques (8)
C-PIB-PET for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI)
18F PET with florbetaben for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
18F PET with flutemetamol for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
18F PET with florbetapir for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI)
Dopamine transporter imaging for the diagnosis of dementia with Lewy bodies
Structural magnetic resonance imaging for the early diagnosis of dementia due to Alzheimer's disease in people with mild cognitive impairment
Regional Cerebral Blood Flow Single Photon Emission Computed Tomography for detection of Frontotemporal dementia in people with suspected dementia
F-FDG PET for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI)
Other diagnostic tests (25)
Mini-Cog for the detection of dementia within a community setting
Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the detection of dementia within community dwelling populations
Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the detection of dementia within a general practice (primary care) setting
Diagnostic test accuracy of telehealth assessment for dementia and mild cognitive impairment
Anticholinergic burden for prediction of cognitive decline or neuropsychiatric symptoms in older adults with mild cognitive impairment or dementia (protocol stage)
Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the detection of dementia within a secondary care setting
Mini-Mental State Examination (MMSE) for the early detection of dementia in people with mild cognitive impairment (MCI)
Clinical judgement by primary care physicians for the diagnosis of all-cause dementia or cognitive impairment in symptomatic people (protocol stage)
Confusion Assessment Method for the intensive care unit (CAM-ICU) for the diagnosis of delirium in adults in critical care settings (protocol stage)
Depression rating scales for detection of major depression in people with dementia (protocol stage)
Diagnostic test accuracy of self-administered cognitive assessment questionnaires for dementia (protocol stage)
Educational interventions for improving the skills of medical practitioners to detect, diagnose, and manage people with cognitive impairment and dementia (protocol stage)
Diagnostic test accuracy of remote, multidomain cognitive assessment (telephone and video call) for dementia
Addenbrooke’s Cognitive Examination III (ACE-III) and mini-ACE for the detection of dementia and mild cognitive impairment
Plasma and cerebrospinal fluid ABeta42 for the differential diagnosis of Alzheimer's disease dementia in participants diagnosed with any dementia subtype in a specialist care setting
AD-8 for detection of dementia across a variety of healthcare settings
Mini-Cog for the detection of dementia within a secondary care setting
Mini-Cog for the detection of dementia within a primary care setting
Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations
Montreal Cognitive Assessment for the detection of dementia
Multi-domain prognostic models used in middle aged adults without known cognitive impairment for predicting subsequent dementia (protocol stage)
Plasma and cerebrospinal fluid amyloid beta for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
CSF tau and the CSF tau/ABeta ratio for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome
Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the early detection of dementia across a variety of healthcare settings
End of Life Care (1)
Palliative care interventions in advanced dementia
Enhancement of normal cognitive function (12)
Acetyl-l-carnitine (fast creative energy) (1)
L-carnitine for cognitive enhancement in people without cognitive impairment
Adrafinil (alertness without stimulation) (0)
Amphetamines (weight loss and energy) (0)
Bacopa monniera (0)
Caffeine (alertness, well-being and energy) (0)
Carbohydrates (1)
Carbohydrates for improving the cognitive performance of independent-living older adults with normal cognition or mild cognitive impairment
Carnosine (protects against dementia, longivity) (0)
Coenzyme Q (fountain of youth) (0)
Cognitive training (1)
Cognition-based interventions for healthy older people and people with mild cognitive impairment
Creatine (0)
Creatine (0)
Curcumin (0)
Dehydroepiandrosterone (DHEA) (1)
Dehydroepiandrosterone (DHEA) supplementation for cognitive function in healthy elderly people
Deprenyl (anti-ageing) (0)
DH3 (memory, concentration and mental endurance) (0)
Diabetes management (1)
Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia
Dilantin (intelligence and concentration) (0)
Dimetheyaaminoethanol (DMAE) (brain enhancement) (0)
Folic acid (1)
Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people
Ginkgo biloba (relief side effects of ageing) (0)
Gerovital (concentration and vitality) (1)
Procaine treatments for cognition and dementia
Green tea (0)
HRT (1)
Hormone replacement therapy for cognitive function in postmenopausal women
Hydergine (intelligence improver) (0)
Hypericum (perception and clear thinking) (0)
Idebenone (cognition and energy enhancement (0)
Liposerine (memory, emotional well-being) (0)
Lucidril (anti-ageing) (0)
Melatonin (anti-ageing) (0)
Modafinil (0)
Nicergoline (clarity and perception) (0)
Omega-3 fish oils (cognition) (1)
Omega 3 fatty acid for the prevention of cognitive decline and dementia
Phosphatidyl serine (0)
Physostigmine (1)
Physostigmine for dementia due to Alzheimer's disease
Picamilone (stimulates without aggression or sedative effect) (0)
Piracetam (intelligence booster) (0)
Pregnonelone (memory enhancement) (0)
Pyritinol (memory, vigilance, concentration) (0)
Pyroglutamic acid (0)
Ritalin (0)
Thiazolidinediones (0)
Vinpocetine (memory enhancer) (0)
Xanthinol nicotinate (reaction speed, memory) (0)
Physical activity (2)
Aerobic exercise to improve cognitive function in older people without known cognitive impairment
Dance movement therapy for dementia
testosterone (0)
Improving cognition (7)
Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without dementia (protocol stage)
Cognitive training interventions for dementia and mild cognitive impairment in Parkinson’s disease
Exergaming for dementia and mild cognitive impairment (protocol stage)
Non-invasive brain stimulation for improving cognitive function in people with dementia and mild cognitive impairment (protocol stage)
Non-invasive brain stimulation for treatment of severe disorders of consciousness in people with acquired brain injury (protocol stage)
Non-pharmacological interventions for improving language and communication in people with primary progressive aphasia: a network meta-analysis (protocol stage)
Psychological interventions for persisting postconcussion symptoms following traumatic brain injury (protocol stage)
Modifiable Risk Factors (13)
Antihypertensive withdrawal for the prevention of cognitive decline
Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively healthy people in late life
Computerised cognitive training for maintaining cognitive function in cognitively healthy people in midlife
Computerised cognitive training for preventing dementia in people with mild cognitive impairment
Dietary interventions for maintaining cognitive function in cognitively healthy people in late life (protocol stage)
Dietary interventions for maintaining cognitive function in cognitively healthy people in mid life (protocol stage)
Dietary interventions for prevention of dementia in people with mild cognitive impairment (protocol stage)
Exercise interventions for maintaining cognitive function in cognitively healthy people in late life (protocol stage)
Exercise interventions for maintaining cognitive function in cognitively healthy people in mid life (protocol stage)
Statin withdrawal in people with dementia
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid life (protocol stage)
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment
Prevention of dementia (36)
Cognitively impaired (22)
Non-pharmacological interventions (3)
Acupuncture (0)
Cognitive training (1)
Cognition-based interventions for healthy older people and people with mild cognitive impairment
Diabetes managament (1)
Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia
Physical activity (1)
Multi-domain interventions for the prevention of dementia and cognitive decline
Prevention trials (0)
Pharmacological interventions (19)
Diabetes management (2)
Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia
Multi-domain interventions for the prevention of dementia and cognitive decline
Donepezil (2)
Cholinesterase inhibitors for mild cognitive impairment
Donepezil for mild cognitive impairment
Folic acid (1)
Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people
Galantamine (3)
Cholinesterase inhibitors for mild cognitive impairment
Galantamine for Alzheimer's disease and mild cognitive impairment
Galantamine for vascular cognitive impairment
Gingko biloba (1)
Ginkgo biloba for cognitive impairment and dementia
Lecithin (1)
Lecithin for dementia and cognitive impairment
Melatonin (1)
Melatonin for the treatment of dementia
Nicergoline (1)
Nicergoline for dementia and other age associated forms of cognitive impairment
Piracetam (1)
Piracetam for dementia or cognitive impairment
Prevention trials (0)
Procaine (Gerovital) (1)
Procaine treatments for cognition and dementia
Rivastigmine (1)
Cholinesterase inhibitors for mild cognitive impairment
Vinpocetine (1)
Vinpocetine for cognitive impairment and dementia
Vitamin B12 (1)
Vitamin B12 for cognition
Vitamin B6 (1)
Vitamin B6 for cognition
Vitamin E (1)
Vitamin E for Alzheimer's dementia and mild cognitive impairment
Non-cognitively impaired (14)
Non-pharmacological interventions (3)
Cognitive training (1)
Cognition-based interventions for healthy older people and people with mild cognitive impairment
Diabetes management (1)
Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia
Diet and lifestyle (1)
Pharmacological treatment of hypertension in people without prior cerebrovascular disease for the prevention of cognitive impairment and dementia
Massage and touch (0)
Physical activity (0)
Prevention trials (0)
Pharmacological interventions (11)
Acetyl-l-carnitine (1)
L-carnitine for cognitive enhancement in people without cognitive impairment
Anti-hypertensives (1)
Pharmacological treatment of hypertension in people without prior cerebrovascular disease for the prevention of cognitive impairment and dementia
Aspirin and NSAIDs (1)
Aspirin and other non-steroidal anti-inflammatory drugs for the prevention of dementia
Dehydroepiandrosterone (DHEA) (1)
Dehydroepiandrosterone (DHEA) supplementation for cognitive function in healthy elderly people
Diabetes management (1)
Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia
Donepezil (0)
Folic acid (1)
Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people
Galantamine (0)
HRT (1)
Hormone replacement therapy for cognitive function in postmenopausal women
Omega-3 fish oil (1)
Omega 3 fatty acid for the prevention of cognitive decline and dementia
Prevention trials (0)
Procaine (Gerovital) (1)
Procaine treatments for cognition and dementia
Rivastigmine (0)
Statins (1)
Statins for the prevention of dementia
Vitamin B12 (0)
Vitamin B6 (1)
Vitamin B6 for cognition
Treatment of Dementia (3)
Cannabinoids for the treatment of dementia
Simulated presence therapy for dementia
Souvenaid for Alzheimer's disease